Dr Heather Angus-Leppan

Job title

Consultant neurologist

Related services

Neurosciences

Location

Royal Free Hospital

Biography

Dr Angus-Leppan MBBS (Hons), MSc (Epilepsy), MD, FRACP, FRCP is consultant neurologist, and epilepsy lead at the Royal Free London NHS Foundation Trust and honorary consultant neurologist, National Hospital, University College London. She is an honorary senior lecturer at University College and Imperial College London.

She has a keen and active interest in general neurology, headache and migraine, epilepsy and chronic pain. Her practice has been enhanced by a wide experience in the northern and southern hemispheres, having worked in Australia, Chile, South Africa and the United Kingdom.

After completing an MD in Sydney, Australia, she came as visiting Australasian clinical fellow to the Radcliffe Infirmary in Oxford in 1993, and subsequently worked as senior registrar in Cardiff, and as a consultant neurologist and honorary senior lecturer at the Essex Neuroscience Centre.

She is current President of the Clinical Neurosciences Section, Royal Society of Medicine.

Languages

English

German

Spanish

Australian

GMC number

3648540

• Angus Leppan, H., Lambert, G.A., Boers, P., Lance, J.W., & Zagami, A.S. (1989) The cervical spinal cord is a relay centre for the central nervous system processing of nociceptor input from the cranial vasculature. Cephalalgia, 9, Suppl 10, 137 138.
• Sachdev, P., Smith, J.S., Angus Lepan, H., & Rodriguez, P. (1990) Pseudodementia 12 years on. J Neurol. Neurosurg. & Psychiatry, 53, 254 259. (Note: mis-spelling of my surname as Angus-Lepan)
• Angus Leppan, H., & Burke, D. (1992) The function of large and small nerve fibres in renal failure. Muscle and Nerve,15, 288 294.
• Angus Leppan, H., Lambert, G.A., Boers, P., Zagami, A.S., & Olausson, B. (1992) Craniovascular nociceptive pathways relay in the upper cervical spinal cord in the cat. Neuroscience Letters, 137, 203 206.
• Lambert, G.A., Lowy, A., Boers, P., Angus Leppan, H., & Zagami, A.S. (1992) The spinal cord processing of input from the superior sagittal sinus: pathway and modulation by ergot alkaloids. Brain Research, 597, 321 330.
• Angus Leppan, H., & Colebatch, J. (1994) Dopamine: Clinical applications in neurology. Australian Prescriber 1, 21 23.
• Angus Leppan, H., Olausson, B., Boers, P., & Lambert, G.A. (1994) Convergence of afferents from superior sagittal sinus and tooth pulp on cells in the upper cervical spinal cord of the cat. Neuroscience Letters, 182, 275 278.
• Angus Leppan, H., Olausson, B., Boers, P., & Lambert, G.A. (1995) Convergence of afferents from superior sagittal sinus and tooth pulp on cells in the thalamus of the cat. Cephalalgia, 15, 191 199.
• Angus Leppan, H., Lambert, G.A., & Michalicek, J. (1997) Convergence of superior sagittal sinus and occipital nerve input in the cervical spinal cord of the cat. Cephalalgia, 17, 625-630.
• McCabe DJ, Pereira AC, Clifton A, Bland JM, Brown MM; CAVATAS Investigators. Restenosis after carotid angioplasty, stenting, or endarterectomy in the Carotid and Vertebral Artery Transluminal Angioplasty Study (CAVATAS). Stroke. 2005 Feb;36(2):281-6. Epub 2005 Jan 13. Angus-Leppan, H. Seizures and other adverse events during routine scalp electroencephalography, Clinical Neurophysiology, 2007, 118, 22-30.
• Coward LJ, McCabe DJ, Ederle J, Featherstone RL, Clifton A, Brown MM; CAVATAS Investigators. Long-term outcome after angioplasty and stenting for symptomatic vertebral artery stenosis compared with medical treatment in the Carotid And Vertebral Artery Transluminal Angioplasty Study (CAVATAS): a randomized trial. Stroke. 2007 May;38(5):1526-30. Epub 2007 Mar 29.
• Angus-Leppan, H. Diagnosing epilepsy in neurology clinics: a prospective study. Seizure 2008; 17:431-436.
• Angus-Leppan H., Parsons L. Epilepsy:epidemiology, assessment,natural history.Medicine 2008;36:571-8.
• Parsons L, Angus-Leppan H. Epilepsy management, Medicine 2008; 36: 579-85.
• Angus-Leppan, H. The Association of British Neurologists, Editorial. Advances in Clinical Neuroscience and Rehabilitation, 2008;9: 4.
• Angus-Leppan, H. Transitions in Neurology. Advances in Clinical Neuroscience and Rehabilitation, 2009;9: 25.
• Ederle J, Bonati LH, Dobson J, Featherstone RL, Gaines PA, Beard JD, Venables GS, Markus HS, Clifton A, Sandercock P, Brown MM; CAVATAS Investigators. Endovascular treatment with angioplasty or stenting. Lancet Neurol. 2009;8:898-907.
• Bonati LH, Ederle J, McCabe DJ, Dobson J, Featherstone RL, Gaines PA, Beard JD, Venables GS, Markus HS, Clifton A, Sandercock P, Brown MM; CAVATAS Investigators. Long term risk of carotid restenosis in patients randomly assigned to endovascular treatment or endarterectomy. Lancet Neurol. 2009;8:908-17.
• Angus-Leppan H, Warlow C. Health Records: out of the frying pan? Advances in Clinical Neuroscience and Rehabilitation, 2009; 9: 43-44.
• Angus-Leppan H. In Britain, it’s the good the bad and the ABN. World Neurology, June 2009;5. wfneurology.org/pdfs/worldNeurology/wn_jun09_row.pf. Angus-Leppan H. Challenges Ahead. Advances in Clinical Neuroscience and Rehabilitation, 2010; 10: 44.
• Angus-Leppan H, Leach JP. A new era in neurological consultations. European Journal Neurology. 2010. 17(4):26-7.
• Cole C, Pointu A, Wellsted DM, Angus-Leppan H. A pilot study of the Epilepsy Risk Awareness Checklist (ERAC) in people with epilepsy and learning disabilities. Seizure 2010;19:592-6.
• Angus-Leppan H. Its all Greek: Report on European Congress of Epileptology. Epilepsy Professional. 2010;103:34-5.
• Guiloff, R.J.; Rajakulendran, S.; Angus-Leppan, H. Syncope and Raynaud’s disease. Archives Neurology 2012,69:608-13.
• Angus-Leppan, H. We must warn women about the risks of untreated, or ineffectively treated, epilepsy. British Medical Journal. 2012;6;e1430.
• Angus-Leppan H. Explaining risks to carers. Learning Disability and Epilepsy Review 2012;2:14-5.
• Parker T, Freilich S, Tidswell T, Angus-Leppan H. Hepatic encephalopathy with epilepsia partialis continua: A case report. Seizure 2012;21(10):813-5.
• Angus-Leppan H, Rudge P, Mead, S, Collinge J, Vincent A. Auto-antibodies in sporadic Creutzfeldt-Jakob disease. JAMA Neurology 2013;70(7):919-22. doi:10.1001/jamaneurol.2013.2077.
• Zaccara G, Sisodiya SM, Giovannelli F, Walker MC, Heaney DC, Angus-Leppan H, Wehner T, Eriksson SH, Liu R, Rugg-Gunn F, Shorvon SD, Sander JW. Network Meta-Analysis and the Comparison of Efficacy and Tolerability of Antiepileptic Drugs for Treatment of Refractory Focal Epilepsy. Br J Clin Pharmacol. 2013 Jun 6. doi: 10.1111/bcp.12175.
• Angus-Leppan H. Migraine: mimics, borderlands and chameleons. Pract Neurol. 2013 Oct;13(5):308-18).
• Angus-Leppan H, Rudge P, Mead S, Collinge J, Vincent A. Creutzfeld-jakob disease-reply. JAMA Neurol. 2013 Dec 1;70(12):1589.Bonati LH, Ederle J, Dobson J, Engelter S, Featherstone RL, Gaines PA, Beard JD, Venables GS, Markus HS, Clifton A, Sandercock P, Brown MM; CAVATAS Investigators.Length of carotid stenosis predicts peri-procedural stroke or death and restenosis in patients randomized to endovascular treatment or endarterectomy. Int J Stroke. 2014 Apr;9(3):297-305. doi: 10.1111/ijs.12084. Epub 2013 Jul 29.
• Angus-Leppan H. First Seizure in adults. BMJ. Apr 2014;348:g2470. doi: 10.1136/bmj.g2470.2014.

Research interests include headaches and migraines, epilepsy and syncope (fainting).